تضامنًا مع حق الشعب الفلسطيني |
POLR2L
اذهب إلى التنقل
اذهب إلى البحث
An Error has occured retrieving Wikidata item for infobox POLR2L (RNA polymerase II subunit L) هوَ بروتين يُشَفر بواسطة جين POLR2L في الإنسان.[1]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Acker J، Murroni O، Mattei MG، Kedinger C، Vigneron M (سبتمبر 1996). "The gene (POLR2L) encoding the hRPB7.6 subunit of human RNA polymerase". Genomics. ج. 32 ع. 1: 86–90. DOI:10.1006/geno.1996.0079. PMID:8786124.
قراءة متعمقة
- Jeang KT (1998). "Tat, Tat-associated kinase, and transcription". J. Biomed. Sci. ج. 5 ع. 1: 24–7. DOI:10.1007/BF02253352. PMID:9570510.
- Yankulov K، Bentley D (1998). "Transcriptional control: Tat cofactors and transcriptional elongation". Curr. Biol. ج. 8 ع. 13: R447–9. DOI:10.1016/S0960-9822(98)70289-1. PMID:9651670.
- Romano G، Kasten M، De Falco G، Micheli P، Khalili K، Giordano A (2000). "Regulatory functions of Cdk9 and of cyclin T1 in HIV tat transactivation pathway gene expression". J. Cell. Biochem. ج. 75 ع. 3: 357–68. DOI:10.1002/(SICI)1097-4644(19991201)75:3<357::AID-JCB1>3.0.CO;2-K. PMID:10536359.
- Marcello A، Zoppé M، Giacca M (2002). "Multiple modes of transcriptional regulation by the HIV-1 Tat transactivator". IUBMB Life. ج. 51 ع. 3: 175–81. DOI:10.1080/152165401753544241. PMID:11547919.
- Stevens M، De Clercq E، Balzarini J (2007). "The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention". Med Res Rev. ج. 26 ع. 5: 595–625. DOI:10.1002/med.20081. PMID:16838299.
- Harrich D، McMillan N، Munoz L، Apolloni A، Meredith L (2007). "Will diverse Tat interactions lead to novel antiretroviral drug targets?". Current drug targets. ج. 7 ع. 12: 1595–606. DOI:10.2174/138945006779025338. PMID:17168834.
- Jang KL، Collins MK، Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC". J. Acquir. Immune Defic. Syndr. ج. 5 ع. 11: 1142–7. PMID:1403646.
- Kato H، Sumimoto H، Pognonec P، Chen CH، Rosen CA، Roeder RG (1992). "HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors". Genes Dev. ج. 6 ع. 4: 655–66. DOI:10.1101/gad.6.4.655. PMID:1559613.
- Southgate C، Zapp ML، Green MR (1990). "Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein". Nature. ج. 345 ع. 6276: 640–2. DOI:10.1038/345640a0. PMID:2190099.
- Wu-Baer F، Sigman D، Gaynor RB (1995). "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat". Proc. Natl. Acad. Sci. U.S.A. ج. 92 ع. 16: 7153–7. DOI:10.1073/pnas.92.16.7153. PMC:41297. PMID:7638159.
- Shpakovski GV، Acker J، Wintzerith M، Lacroix JF، Thuriaux P، Vigneron M (1995). "Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae". Mol. Cell. Biol. ج. 15 ع. 9: 4702–10. PMC:230713. PMID:7651387.
- Herrmann CH، Rice AP (1995). "Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor". J. Virol. ج. 69 ع. 3: 1612–20. PMC:188757. PMID:7853496.
- McKune K، Moore PA، Hull MW، Woychik NA (1996). "Six human RNA polymerase subunits functionally substitute for their yeast counterparts". Mol. Cell. Biol. ج. 15 ع. 12: 6895–900. PMC:230944. PMID:8524256.
- Keen NJ، Gait MJ، Karn J (1996). "Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 6: 2505–10. DOI:10.1073/pnas.93.6.2505. PMC:39827. PMID:8637904.
- Yang X، Herrmann CH، Rice AP (1996). "The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function". J. Virol. ج. 70 ع. 7: 4576–84. PMC:190394. PMID:8676484.
- Agostini I، Navarro JM، Rey F، Bouhamdan M، Spire B، Vigne R، Sire J (1996). "The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB". J. Mol. Biol. ج. 261 ع. 5: 599–606. DOI:10.1006/jmbi.1996.0485. PMID:8800208.
- Zhou Q، Sharp PA (1996). "Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat". Science. ج. 274 ع. 5287: 605–10. DOI:10.1126/science.274.5287.605. PMID:8849451.
- Okamoto H، Sheline CT، Corden JL، Jones KA، Peterlin BM (1996). "Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 21: 11575–9. DOI:10.1073/pnas.93.21.11575. PMC:38099. PMID:8876177.
- Chun RF، Jeang KT (1996). "Requirements for RNA polymerase II carboxyl-terminal domain for activated transcription of human retroviruses human T-cell lymphotropic virus I and HIV-1". J. Biol. Chem. ج. 271 ع. 44: 27888–94. DOI:10.1074/jbc.271.44.27888. PMID:8910388.