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SERPINI1
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An Error has occured retrieving Wikidata item for infobox SERPINI1 (Serpin family I member 1) هوَ بروتين يُشَفر بواسطة جين SERPINI1 في الإنسان.[1][1]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ أ ب "Entrez Gene: SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1". مؤرشف من الأصل في 2010-03-07.
قراءة متعمقة
- Yepes M؛ Lawrence DA (2004). "Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system". Thromb. Haemost. ج. 91 ع. 3: 457–64. DOI:10.1160/TH03-12-0766. PMID:14983220.
- Schrimpf SP، Bleiker AJ، Brecevic L، وآخرون (1997). "Human neuroserpin (PI12): cDNA cloning and chromosomal localization to 3q26". Genomics. ج. 40 ع. 1: 55–62. DOI:10.1006/geno.1996.4514. PMID:9070919.
- Hastings GA، Coleman TA، Haudenschild CC، وآخرون (1998). "Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival". J. Biol. Chem. ج. 272 ع. 52: 33062–7. DOI:10.1074/jbc.272.52.33062. PMID:9407089.
- Davis RL، Shrimpton AE، Holohan PD، وآخرون (1999). "Familial dementia caused by polymerization of mutant neuroserpin". Nature. ج. 401 ع. 6751: 376–9. DOI:10.1038/43894. PMID:10517635.
- Chang WS، Chang NT، Lin SC، وآخرون (2000). "Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26". Genes Chromosomes Cancer. ج. 29 ع. 3: 240–55. DOI:10.1002/1098-2264(2000)9999:9999<::AID-GCC1029>3.0.CO;2-A. PMID:10992299.
- Belorgey D؛ Crowther DC؛ Mahadeva R؛ Lomas DA (2002). "Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro". J. Biol. Chem. ج. 277 ع. 19: 17367–73. DOI:10.1074/jbc.M200680200. PMID:11880376.
- Davis RL، Shrimpton AE، Carrell RW، وآخرون (2002). "Association between conformational mutations in neuroserpin and onset and severity of dementia". Lancet. ج. 359 ع. 9325: 2242–7. DOI:10.1016/S0140-6736(02)09293-0. PMID:12103288.
- Barker-Carlson K؛ Lawrence DA؛ Schwartz BS (2003). "Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro". J. Biol. Chem. ج. 277 ع. 49: 46852–7. DOI:10.1074/jbc.M207740200. PMID:12228252.
- Parmar PK، Coates LC، Pearson JF، وآخرون (2002). "Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". J. Neurochem. ج. 82 ع. 6: 1406–15. DOI:10.1046/j.1471-4159.2002.01100.x. PMID:12354288.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Miranda E؛ Römisch K؛ Lomas DA (2004). "Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum". J. Biol. Chem. ج. 279 ع. 27: 28283–91. DOI:10.1074/jbc.M313166200. PMID:15090543.
- Teesalu T، Kulla A، Simisker A، وآخرون (2005). "Tissue plasminogen activator and neuroserpin are widely expressed in the human central nervous system". Thromb. Haemost. ج. 92 ع. 2: 358–68. DOI:10.1267/THRO04080358. PMID:15269833.
- Belorgey D، Sharp LK، Crowther DC، وآخرون (2004). "Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB". Eur. J. Biochem. ج. 271 ع. 16: 3360–7. DOI:10.1111/j.1432-1033.2004.04270.x. PMID:15291813.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Onda M؛ Belorgey D؛ Sharp LK؛ Lomas DA (2005). "Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies". J. Biol. Chem. ج. 280 ع. 14: 13735–41. DOI:10.1074/jbc.M413282200. PMID:15664988.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. Bibcode:2005Natur.437.1173R. DOI:10.1038/nature04209. PMID:16189514.
- Kinghorn KJ، Crowther DC، Sharp LK، وآخرون (2006). "Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease". J. Biol. Chem. ج. 281 ع. 39: 29268–77. DOI:10.1074/jbc.M600690200. PMID:16849336.
- Chen PY، Chang WS، Chou RH، وآخرون (2007). "Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner". BMC Mol. Biol. ج. 8: 2. DOI:10.1186/1471-2199-8-2. PMC:1796892. PMID:17212813.
- Gourfinkel-An I، Duyckaerts C، Camuzat A، وآخرون (2007). "Clinical and neuropathologic study of a French family with a mutation in the neuroserpin gene". Neurology. ج. 69 ع. 1: 79–83. DOI:10.1212/01.wnl.0000265052.99144.b5. PMID:17606885.