English: Gif converted from movie: normal (top) and aβ applied (bottom) simulations 2 ms after the peak of the somatic spike. On the left are plots of instantaneous membrane potential along paths from the soma (0 μm) to a distal dendritic tuft compartment (849 μm) and oblique dendrites (x-axis in μm, y-axis in mV, paths shown in left panel of Figure 1B ). The figures on the right display membrane potential throughout the model at the corresponding time. At this instant the bAP has died out in the normal model, but it continues to propagate into the apical tree of the aβ-applied model. (Abnormal excitability of oblique dendrites implicated in early Alzheimer’s: a computational study http://www.frontiersin.org/Journal/10.3389/fncir.2010.00016/full)